Bioprocess Development Engineer

We are seeking a highly motivated bio-process development engineer to join a translational academic lab focused on the large-scale production of lab-grown red blood cells (lgRBCs). This role lies at the intersection of stem cell biology, erythropoiesis, and bioprocess engineering, with direct applications in transfusion medicine and cell-based therapeutics.

WORK ACTIVITIES

• Drive the development of scalable red blood cell manufacturing platforms
• Culture and differentiate stem or progenitor cells under defined conditions
• Apply CRISPR/Cas9 genome editing to engineer erythroid cells
• Design and operate bioreactor systems for high-density perfusion culture
• Optimize protocols for erythroid differentiation, expansion, and harvest
• Contribute to experimental design, data analysis, and manuscript preparation
• Collaborate with internal and external partners on translational applications
• Maintain clear documentation and assist in grant and patent applications

Bachelor's degree in Biotechnology with 3 years experience; Master's degree preferred.

EXPERIENCE REQUIRED

• Extensive experience with mammalian cell culture (stem/progenitor cells preferred)
• Demonstrated ability to work independently and solve complex problems
• Familiarity with erythroid biology, iPSC/HSPC differentiation, or hematopoiesis
• Proficiency with genome editing tools such as CRISPR/Cas9
• Experience with bioreactor systems, perfusion culture, or bioprocess scale-up
• Engineering background in bioengineering, chemical engineering, or related field
• Experience working in biotech, CDMO, or GMP-adjacent environments

PREFERRED QUALIFICATION

• Familiarity with red blood cell phenotyping or transfusion medicine
• Prior involvement in translational or interdisciplinary research projects
• Interest in commercialization and startup participation